I'll start by admitting how much I love the Sonogashira coupling. It's a fun reaction, and it LOVES my substrates. Plus, it gives me an excuse to make Pd(Ph3P)4. Making tetrakis is one of those things you can do on a particularly bad lab day that is guaranteed to make you feel better. It's very hard to screw up, and you get shiny yellow crystals. Anyway, I set three of these up the other day:
If you were wondering, yes, there appears to be a shortage of tiny little clamps in my lab. We just don't do much with 14/20 glassware (this is an exception of sorts). Maybe they're in the stockroom, but by the time I need one I'm always in the middle of setting something up, so I haven't checked. Yes, my oil bath is nasty looking. It was like that when I inherited it from the hood's previous occupant. The color reminds me of motor oil, which is a quick way to ick me out a little.
It looked exactly like metallic copper, which it doesn't quite in the picture, but close enough. Does anyone know what it could be? I've seen palladium plate out of a reaction, but copper? That just seems weird. It worked, though, so I'm not complaining.
I took all three of those through silica plugs, which was more time-consuming than I would have liked. I know this is pretty routine, and barely worth reading about, but since some chemists seem to be complaining about the lack of pretty colors in their lives, I had to show mine off. (You have permission to be jealous now.) Here is one of the fractions I collected:
I know blue isn't too much to be excited about in the way of fluorescence (yeah, yeah, emission probability goes as ν3, I know, red is cooler) but it's still surprising to look at a TLC plate and be distracted by an unexpected glow from elsewhere on the bench.
 And then you wash them with ether. Mmm. Keeps getting better and better, doesn't it?